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Required safety monitoring for men on or starting Testosterone Replacement Therapy (TRT). This comprehensive panel ensures TRT is working effectively while monitoring for potential side effects on blood counts, organ function, cardiovascular health, and other hormones that can be affected by treatment.
The primary male sex hormone governing energy, libido, muscle mass, mood, and bone health. Measuring total testosterone is the foundation for identifying hormonal imbalances, testosterone deficiency, or conditions such as hypogonadism.
The biologically active fraction of testosterone your body can use. Provides a more accurate assessment of hormonal status, particularly where symptoms exist but total testosterone appears within normal range.
A protein that binds testosterone and affects how much is available to your tissues. SHBG levels are essential for interpreting total and free testosterone results in full clinical context.
In men, FSH supports sperm production in the testes. Abnormal levels can indicate fertility issues, testicular dysfunction, or pituitary conditions affecting reproductive health.
Signals the testes to produce testosterone. LH levels help determine whether low testosterone originates in the testes or in the brain's hormonal signaling, a clinically important distinction for diagnosis and treatment planning.
A pituitary hormone that, when elevated in men, can suppress testosterone, reduce libido, and contribute to erectile dysfunction. Raised prolactin may also indicate a pituitary condition requiring further investigation.
Men produce small amounts of oestradiol through the natural conversion of testosterone. Elevated levels can cause symptoms including reduced libido, erectile dysfunction, mood changes, and gynaecomastia (breast tissue development), and are particularly relevant for men on testosterone therapy.
Fats circulating in your blood that provide energy but, at elevated levels, increase cardiovascular risk. High triglycerides are often linked to diet, alcohol, insulin resistance, and metabolic syndrome.
An overall measure of cholesterol in your blood. While some cholesterol is essential, elevated levels increase the risk of arterial disease, heart attack, and stroke, particularly alongside other risk factors.
All cholesterol except the protective HDL type, providing a comprehensive view of potentially harmful cholesterol that can accumulate in artery walls over time.
Often called 'bad' cholesterol, LDL is the primary driver of plaque build-up in arteries. Men face higher cardiovascular risk than women at equivalent ages, making LDL monitoring an important part of preventive health.
Often called 'good' cholesterol, HDL transports excess cholesterol away from the arteries. Higher HDL levels are associated with reduced cardiovascular risk.
A widely used cardiovascular risk indicator that balances total cholesterol against protective HDL. A lower ratio reflects better heart health and is an important overall risk assessment tool.
An essential electrolyte regulating fluid balance and blood pressure. Abnormal sodium can indicate kidney problems, dehydration, or underlying hormonal issues.
A waste product filtered by the kidneys from protein breakdown. Elevated BUN can indicate reduced kidney function, dehydration, or high protein intake.
A waste product of muscle activity, filtered by the kidneys. Elevated creatinine is a key indicator of reduced kidney function and is assessed alongside eGFR for a complete picture.
eGFR (Estimated Glomerular Filtration Rate)
Measures all proteins in your blood, reflecting nutritional status and the health of your liver and kidneys. Abnormal levels can point to liver disease, kidney problems, or nutritional deficiencies.
The main protein in your blood and a key carrier of testosterone. Albumin levels are used in the calculation of free testosterone and also reflect general nutritional status and liver health.
An enzyme found in the liver, bones, and bile ducts. Elevated ALP can signal liver disease, bile duct obstruction, or bone conditions.
A liver enzyme that rises when liver cells are damaged. Assessed alongside ALT to identify liver inflammation, injury, or disease.
The most specific marker of liver cell damage. Elevated ALT is commonly caused by fatty liver disease, alcohol use, medication effects, or viral hepatitis.
A pigment produced when red blood cells break down, processed and excreted by the liver. Elevated bilirubin can cause jaundice and indicate liver disease, bile duct problems, or increased red cell breakdown.
A group of proteins produced by the liver and immune system. Abnormal globulin levels can indicate liver disease, immune conditions, or chronic inflammation.
A liver enzyme particularly sensitive to alcohol consumption, medication use, and bile duct conditions. Often used alongside other liver markers to build a fuller picture of liver health.
Reflects your average blood sugar levels over the past two to three months. Used to diagnose and monitor type 2 diabetes and pre-diabetes - a clinically important marker given the strong association between insulin resistance and testosterone deficiency in men.
A protein produced by the prostate gland. PSA levels support screening for prostate conditions including benign enlargement and prostate cancer, and provide an important baseline for men considering or currently on testosterone therapy.
A broad assessment of red cells, white cells, and platelets. The FBC can detect anaemia, infection, inflammation, and blood disorders. Particularly relevant for men on testosterone therapy, where elevated red blood cell counts (polycythaemia) are a recognised monitoring priority.
Why it matters
Low testosterone affects more men than you think.
Studies estimate that 40% of men in the UK have lower than optimal testosterone levels¹² — yet most don't know it. Symptoms are easy to dismiss as tiredness or stress.
Fatigue
Low mood
Low libido
Muscle loss
Brain fog
Poor sleep
How it works
A clear path from test to treatment.
Order online, collect your sample at home in the morning (between 7–11am), and return by post. We test a comprehensive panel of markers to get a full picture of your hormonal health.
Your sample is analysed by aUKAS-accredited laboratory. A clinician reviews your results and releases them to your patient portal within2–5 working days, with a plain-English written explanation.
Clinical guidelines require two separate early morning tests, taken at least two weeks apart, before a diagnosis of low testosterone can be confirmed. If your first test indicates low T, we’ll send you a kit for your second test.This second test is a venous blood draw -you can either book a home visit via our partner Heim, or arrange for someone you know (such as a local nurse or phlebotomist) to take the sample using the kit provided. Payment for the second test is taken first; you’ll then receive a link by email to book your Heim appointment if needed.
If both tests confirm low testosterone and treatment is clinicallyappropriate, your prescriber will issue apersonalisedTRT plan. Medication is dispensed by our GPhC-registered pharmacy partner,Mediva, and delivered to your door.
Treatment doesn’t stop at prescription. You’ll have regular follow-up blood tests and clinical check-ins throughout your treatment to ensure your levels remain safe and effective.