GLP-1 medications have transformed the way obesity and weight management are treated in the UK. Originally developed to help people with type 2 diabetes, these prescription medicines are now widely used to support sustainable weight loss alongside healthy lifestyle changes.

Whether you've heard of Mounjaro, Wegovy, Ozempic, or the newly approved Wegovy tablet, understanding the differences between them can help you make an informed decision.

In this guide, we'll explain the most popular GLP-1 medications available in the UK, how they work, and how Cannaray Wellness can help you access clinically supervised treatment safely.

What is a GLP-1 medication?

GLP-1 stands for Glucagon-Like Peptide-1, a hormone naturally produced in your gut after eating.

GLP-1 medications work by:

• Reducing appetite
• Helping you feel fuller for longer
• Slowing the rate your stomach empties
• Reducing food cravings
• Improving blood sugar regulation

Some newer medications, such as Mounjaro, also activate a second hormone called GIP, which may improve weight loss outcomes for some people.

The most popular GLP-1 medications in the UK

1. Mounjaro (Tirzepatide)

Mounjaro has quickly become one of the UK's most requested prescription weight loss treatments.

Unlike traditional GLP-1 medications, Mounjaro works on both the GLP-1 and GIP receptors, helping regulate appetite while improving metabolic function.

Benefits

• Weekly injection
• May lead to significant weight loss when combined with healthy lifestyle changes
• Helps reduce hunger throughout the week
• Often suitable for people with obesity or weight-related health conditions

Clinical studies have shown that tirzepatide can achieve some of the highest average weight loss among currently licensed medicines.

2. Wegovy (Semaglutide Injection)

Wegovy remains one of the best-known GLP-1 medications in the UK.

Containing semaglutide, Wegovy is taken as a once-weekly injection and has been prescribed to thousands of people looking for medically supervised weight management.

Benefits

• Weekly injection
• Proven appetite suppression
• Reduces cravings
• Helps patients maintain long-term weight loss when combined with diet and exercise

Wegovy is licensed specifically for chronic weight management in eligible adults.

3. Wegovy Tablet (New for 2026)

One of the biggest developments in weight management is the arrival of the Wegovy tablet.

Approved in the UK in June 2026, it contains the same active ingredient (semaglutide) as the injectable version but is taken as a once-daily tablet.

Why people are interested

• Needle-free alternative
• Daily tablet instead of weekly injection
• Same active ingredient as injectable Wegovy
• Suitable for people who dislike injections or travel frequently

The tablet offers another option for people who prefer oral medication while still receiving clinically supervised treatment.

4. Ozempic

Ozempic also contains semaglutide, but in the UK it is primarily licensed for type 2 diabetes rather than weight management.

Although many people have heard of Ozempic because of media attention, healthcare professionals generally prescribe Wegovy when the primary goal is weight loss.

5. Saxenda (Liraglutide)

Before Wegovy became widely available, Saxenda was one of the leading GLP-1 weight loss medications.

It remains available in some cases, although many clinics now offer newer treatments that require fewer injections.

Key differences

• Daily injection
• Proven weight loss support
• Older generation GLP-1 medication

Which GLP-1 medication is best?

There isn't a single "best" medication for everyone.

The right choice depends on several factors, including:

• Your BMI
• Medical history
• Existing health conditions
• Previous weight loss treatments
• Lifestyle
• Whether you prefer injections or tablets

A qualified clinician should always assess your eligibility before prescribing any GLP-1 medication.

Who can access GLP-1 treatment in the UK?

Private clinics may prescribe GLP-1 medications following a clinical assessment if you meet the eligibility criteria.

This usually includes:

• Completing a medical questionnaire
• Providing relevant medical information
• Sharing photos where appropriate
• Clinical review by an independent prescriber

Eligibility is assessed individually, and treatment decisions are based on your overall health, not just your BMI.

GLP-1 treatment at Cannaray Wellness

At Cannaray Wellness, we believe weight management should be personalised, clinically supervised, and straightforward.

Our online pathway has been designed to make starting treatment as simple as possible.

With Cannaray Wellness, you can:

• Complete a short online eligibility questionnaire in around 4 minutes
• Upload your required photos directly through the secure platform
• Receive an independent clinical assessment
• Access treatments including Mounjaro, Wegovy, and the new Wegovy tablet (subject to clinician approval and availability)
• Receive ongoing support throughout your weight loss journey

We also believe transparency matters. That's why you'll always see clear pricing, with no hidden fees or unexpected changes between your first and future treatment orders.

Can blood tests help before starting GLP-1 treatment?

While not everyone requires blood testing before treatment, understanding your health can be valuable.

Cannaray Wellness also offers at-home blood tests that can help assess important health markers, providing additional insight into your overall wellbeing before or during your weight management journey.

Frequently Asked Questions

What is the newest GLP-1 medication in the UK?

The newest option is the Wegovy tablet, approved in June 2026 as the first oral semaglutide treatment licensed for weight management in the UK.

Is Mounjaro better than Wegovy?

Both medications are highly effective. Some clinical studies suggest Mounjaro may lead to greater average weight loss, but the best option depends on individual circumstances and should be determined by a clinician.

Can I buy GLP-1 medications without a prescription?

No. GLP-1 medications are prescription-only medicines in the UK and should only be obtained through regulated healthcare providers following a clinical assessment.

How do I know if I'm eligible?

The quickest way is to complete a clinical eligibility questionnaire through a regulated provider such as Cannaray Wellness. A qualified clinician will review your information before making any prescribing decision.